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The Global Flourishing Study is generously funded by the David & Carol Myers Foundation, Fetzer Institute, the John Templeton Foundation, the Paul Foster Family Foundation, Templeton Religion Trust, Templeton World Charity Foundation, Well-Being for Planet Earth, and the Well Being Trust.

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Happiness & Life Satisfaction20266 min read

Is 'Not Depressed' the Same as Happy?

Mental illness, mental health, and mental well-being

Notable finding

High well-being linked to up to 90% lower depression risk.

By
VanderWeele, Tyler J. et al.
Participants
240,000
Countries
22
Journal
npj Mental Health Research
DOI
10.1038/s44184-026-00193-7
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Chat with paper
§1

Key Takeaways

01

Mental health should be understood as more than just the absence of mental illness, as it also includes positive aspects of well-being like happiness and a sense of purpose.

02

Research shows that a person can experience mental illness while still reporting high levels of positive well-being, and conversely, someone without a mental illness can still lack a sense of flourishing.

03

Promoting positive mental well-being through practices like gratitude or acts of kindness is valuable on its own and can also serve as a powerful tool for preventing and treating mental illness.

§2

Why It Matters

Mental health is not simply the absence of pain but the active cultivation of joy, meaning, and connection in our lives.

This research matters because it challenges how healthcare systems, governments, and even everyday people think about mental health. If we only track and treat mental illness, we miss the chance to understand what helps people truly thrive. The paper calls for national and global data collection on positive mental well-being — not just depression and anxiety rates. It also suggests that low-cost, community-based practices like gratitude exercises, acts of kindness, and forgiveness workbooks could be distributed in schools, clinics, and neighborhoods to promote well-being and potentially prevent mental illness before it starts. Within mental healthcare specifically, clinicians could ask patients about meaning, purpose, and life goals — not just symptoms. The authors argue this is not a zero-sum choice: paying attention to positive well-being could actually increase interest and funding for both sides of mental health. For a world spending enormous resources on mental illness treatment, this perspective suggests we are leaving a powerful, affordable tool unused.

This research matters because it challenges how healthcare systems, governments, and even everyday people think about mental health. If we only track and treat mental illness, we miss the chance to understand what helps people truly thrive. The paper calls for national and global data collection on positive mental well-being — not just depression and anxiety rates. It also suggests that low-cost, community-based practices like gratitude exercises, acts of kindness, and forgiveness workbooks could be distributed in schools, clinics, and neighborhoods to promote well-being and potentially prevent mental illness before it starts. Within mental healthcare specifically, clinicians could ask patients about meaning, purpose, and life goals — not just symptoms. The authors argue this is not a zero-sum choice: paying attention to positive well-being could actually increase interest and funding for both sides of mental health. For a world spending enormous resources on mental illness treatment, this perspective suggests we are leaving a powerful, affordable tool unused.

Mental health is not simply the absence of pain but the active cultivation of joy, meaning, and connection in our lives.

§3

The Story

When we hear "mental health," most of us think about not being sick — not being depressed, not having anxiety, not struggling with a disorder. But this paper argues that mental health is really two different things, not one. The first is the absence of mental illness.

A person with no diagnosed illness can still feel empty, just as someone with depression can still find life meaningful.

The second is positive mental well-being — things like happiness, a sense of meaning, good coping, and feeling that life is going well. These two are related, but they are not the same. The authors bring together different kinds of evidence to make their case. Conceptually, knowing someone doesn't have a mental illness doesn't tell us whether they're happy or feel their life has purpose.

Empirically, studies show that some people with depression still report high levels of life satisfaction, and some people with no diagnosis feel stuck or unfulfilled. Data from the Global Flourishing Study, which spans 22 countries, shows that different factors relate to each dimension differently. For example, religious service attendance was much more strongly connected to life satisfaction than to depression, while age was more strongly connected to depression than to life satisfaction. The paper also reviews evidence that positive mental well-being may help prevent future mental illness. People who scored high on well-being measures had a 69–90% lower risk of developing a mental disorder later, even after accounting for their starting point.

The authors argue that we need to measure, study, and promote positive mental well-being alongside our efforts to treat mental illness — not as a replacement, but as a necessary companion.

Figure
69-90%
Reduced Risk of Depression

Individuals without a mental disorder at baseline who scored high on a well-being scale had a 69-90% lower risk of developing depression or another mental disorder.

Figure
2x
Well-being with Depression

Among a group of adults who had experienced a major depressive episode, twice as many reported moderate-to-high positive mental health as those who were considered to lack positive mental health.

Figure
1:5
High vs. Lacking Well-being

Among people who had experienced a major depressive episode, for every one person who still had high positive mental health, about five people were considered to lack positive mental health.

Figures
69-90%
Reduced Risk of Depression

Individuals without a mental disorder at baseline who scored high on a well-being scale had a 69-90% lower risk of developing depression or another mental disorder.

2x
Well-being with Depression

Among a group of adults who had experienced a major depressive episode, twice as many reported moderate-to-high positive mental health as those who were considered to lack positive mental health.

1:5
High vs. Lacking Well-being

Among people who had experienced a major depressive episode, for every one person who still had high positive mental health, about five people were considered to lack positive mental health.

§4

Reader Questions

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Research Details
& Citation

Chat with this paper
Published
2026
Journal
npj Mental Health Research
Participants
240,000
Countries
22
Cite this paper
VanderWeele, T. J., Johnson, B. R., Bradshaw, M., Goodman, D. M., Kubzansky, L. D., Lomas, T., Moreira-Almeida, A., Okafor, C. N., Ouyang, S. T., & Patel, V. (2026). Mental illness, mental health, and mental well-being. Npj Mental Health Research, 5(1). https://doi.org/10.1038/s44184-026-00193-7
Tags
mental healthhappinesslife-satisfactiondepression-anxietylife-meaningsuffering
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